Assembling sequences in a multiple sequence alignment
( = identifying homologous residues)


Textbook readings

Chapter 3, pages 32-39

Notes, Comments and Updates

What's the point?

    1. To be able to describe what a sequence alignment is
    2. To be able to describe how RNA structures are aligned
    3. To be able to draw RNA structures from a structural alignment


In past years in this course, we've covered sequence alignment in great detail. This year we will focus on what an alignment is conceptually, and how structural information in an RNA secondary structure is useful in the alignment process. In other words, I will NOT expect you to be able to align sequences yourself (manually) either on the basis of similarity or structure, as described in the textbook, on the exam.